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Medical Drug Benefit Clinical Criteria Updates

Please note, this communication applies to Healthy Blue + MedicareSM (HMO D-SNP) offered by Blue Cross and Blue Shield of North Carolina (Blue Cross NC).

On November 19, 2021, January 4, 2022, and February 25, 2022, the Pharmacy and Therapeutics (P&T) Committee approved the following Clinical Criteria applicable to the medical drug benefit for Blue Cross and Blue Shield of North Carolina. These policies were developed, revised, or reviewed to support clinical coding edits.

Visit Clinical Criteria* to search for specific policies. If you have questions or would like additional information, use this email.

Please see the explanation/definition for each category of Clinical Criteria below:

  • New: newly published criteria
  • Revised: addition or removal of medical necessity requirements, new document number
  • Updates marked with an asterisk (*) notate that the criteria may be perceived as more restrictive

Please share this notice with other members of your practice and office staff.

Note: The Clinical Criteria listed below applies only to the medical drug benefits contained within the member’s medical policy. This does not apply to pharmacy services.

Effective DateDocument NumberClinical Criteria TitleNew or Revised
July 23, 2022*ING-CC-0211Kimmtrak (tebentafusp-tebn)New
July 23, 2022*ING-CC-0210Enjaymo (sutimlimab-jome)New
July 23, 2022*ING-CC-0213Voxzogo (vosoritide)New
July 23, 2022*ING-CC-0212Tezspire (tezepelumab-ekko)New
July 23, 2022*ING-CC-0086Spravato (esketamine) Nasal SprayRevised
July 23, 2022ING-CC-0157Padcev (enfortumab vedotin)Revised
July 23, 2022ING-CC-0125Opdivo (nivolumab)Revised
July 23, 2022ING-CC-0119Yervoy (ipilimumab)Revised
July 23, 2022*ING-CC-0099Abraxane (paclitaxel, protein bound)Revised
July 23, 2022ING-CC-0120Kyprolis (carfilzomib)Revised
July 23, 2022ING-CC-0126Blincyto (blinatumomab)Revised
July 23, 2022ING-CC-0129Bavencio (avelumab)Revised
July 23, 2022*ING-CC-0090Ixempra (ixabepilone)Revised
July 23, 2022ING-CC-0110Perjeta (pertuzumab)Revised
July 23, 2022ING-CC-0115Kadcyla (ado-trastuzumab)Revised
July 23, 2022ING-CC-0108Halaven (eribulin)Revised
July 23, 2022*ING-CC-0033Xolair (omalizumab)Revised
July 23, 2022*ING-CC-0043Monoclonal Antibodies to Interleukin-5Revised
July 23, 2022ING-CC-0038Human Parathyroid Hormone AgentsRevised
July 23, 2022*ING-CC-0186Margenza (margetuximab-cmkb)Revised
July 23, 2022*ING-CC-0124Keytruda (pembrolizumab)Revised
July 23, 2022*ING-CC-0078Orencia (abatacept)Revised
July 23, 2022ING-CC-0050Monoclonal Antibodies to Interleukin-23Revised
July 23, 2022ING-CC-0042Monoclonal Antibodies to Interleukin-17Revised
July 23, 2022*ING-CC-0029Dupixent (dupilumab)Revised
July 23, 2022*ING-CC-0208Adbry (tralokinumab)Revised
July 23, 2022*ING-CC-0209Leqvio (inclisiran)Revised
July 23, 2022*ING-CC-0166Trastuzumab AgentsRevised
July 23, 2022*ING-CC-0107Bevacizumab for Non-ophthalmologic IndicationsRevised

For more information, visit Healthy Blue + Medicare